Ying L, Talbot CL, Chandravanshi B, Ksiazek A, Chowdhury KH, Maschek JA, Cox J, Satheesh Babu AK, Paz HA, Anandh Babu PV, Meyerholz DK, Wankhade UD, Holland WL, Tai ES, Summers SA Chaurasia B#. Cordyceps inhibits ceramide biosynthesis and improves insulin resistance and hepatic steatosis. Scientific Reports, May;12 (1):7273. # Corresponding author.

Keshvari S, Ceddia PR, Rajbhandari P, Chaurasia B#, Bond ST# (2022). Editorial: Adipose Tissue in Obesity and Metabolic Disease. Frontiers in Physiology. April; (13):898861. Co-Corresponding author.

Jain R, Wade G, Ong I, Chaurasia B, Simcox J (2022). Systemic assessment of lipid profiles determines tissue contribution to circulating lipid pool in cold exposure. Journal of Lipid Research. March; (14): 100197.

Chaurasia B#, Ying, L, Talbot CL, Maschek JA, Cox J, Schuchman HE, Hirabayashi Y, Holland LW, Summers SA (2021). Ceramides are necessary and Sufficient for Diet-Induced Impairment of Brown Adipose Tissue Molecular Metabolism. March; (19): 45:101145. # Corresponding author

Chaurasia B and Summers SA (2021). Sphingolipids in Metabolism: Key lipotoxic players. Annual Review of Physiology. February; (10): 83:303-330. # Shared Corresponding author

Ying L*#, Chaurasia B*#, Kaddai V, Wilkerson JL, Maschek JA, Cox J, Wei P, Bensard C, Meikle JP, Clevers H, Shayman AJ, Hirabayashi Y, Holland WL, Rutter J, Summers SA (2020). Serine Palmitoyltransferase Controls Stemness of Intestinal Progenitors (Biorixv, the preprint server biology) *co-first and # Co-corresponding author

Chaurasia B#, Talbot CL and Summers SA (2020). Adipocyte CeramidesThe Nexus of Inflammation and Metabolic Disease. Frontiers in Immunology. September; (11): 576347. # Corresponding author

Ying L, Talbot CL and Chaurasia B# (2020). Ceramides in Adipose Tissue. Frontiers in Endocrinology. June 19; doi:10.3389/fendo.2020.00407. ecollection 2020. # Corresponding author

Charron MJ, Williams L, Seki Y, Du XQ, Chaurasia B, Saghatelian A, Summers SA, Katz EB, Vuguin PM and Reznik SE (2020). The Molecular Mechanism of Antioxidant Effects of N-acetylcysteine in Mice Programmed for Metabolic Disease. Diabetes. May 2020, db191129.

Summers SA, Chaurasia B and Holland WL (2019). Metabolic Messengers: Ceramides. Nature Metabolism. October 24; doi:10.1038/s42255019-0134-8

Buffolo M, Pires KM, Ferhat M, Llkun O, Makaju A, Achenbach A, Bowman F, Atkinson DL, Holland WL, Amri EZ, Chaurasia B, Franklin S and Boudina S (2019). Identification of a Paracrine Signaling Mechanism Linking CD34high Progenitors to the Regulation of Visceral Fat Expansion and Remodeling. Cell Reports. October; 8(29): 270-282.

Karanth S, Chaurasia B, Bowman FM, Tippetts T, Holland WL, Summers SA and Schlegel A (2019). FOXN3 controls liver glucose metabolism by regulating gluconeogenic substrate selection. Physiological Reports. September; 7(18) e14238.

Chaurasia B, Tippetts T, Monibas RM, Liu J, Li Y, Wang L, Wilkerson JL, Sweeney CR, Pereira RF, Sumida DH, Maschek JA, Cox JE, Kaddai V, Lancaster GI, Siddique MM, Poss A, Pearson M, Satapati S, Zhou H, McLaren DG, Previs SF, Chen Y, Qian Y, Petrov A, Wu M, Shen X, Yao J, Nunes CN, Howard AD, Wang L, Erion MD, Rutter J, Holland WL, Kelley DE, Summers SA. (2019). Targeting a Ceramide Double-Bond Improves Insulin Resistance and Steatohepatitis. Science. July; 365(6451): 386-392.

  • Perspective: Kusminski CM and Scherer PE (2019). Lowering ceramides to overcome diabetes. Science. July; 365(6451): 319-320.
  • Commentary: Samuel VT and Shulman GIS (2019). Nonalcoholic fatty liver disease, insulin resistance, and ceramides. The New England Journal of Medicine. November 7; 381:1866-1869.
  • Commentary: Järvinen HY (2020). Ceramides-a cause of insulin resistance in NAFLD in both murine models and humans. Hepatology.doi:10.1002/hep.31095.

Ying L, Tippetts TS and Chaurasia B# (2019). Ceramide dependent lipotoxicity in metabolic diseases. Nutrition& Healthy aging. 5: 1-12. #Corresponding author

Kiser PD, Kloesnikov AV, Kiser JZ, Dong Z, Chaurasia B, Wang L, Summers SA, Hoang T, Blackshaw S, Peachey NS, Kefalov VJ, Palczewski K, (2019). Conditional deletion of Des1 in the mouse retina does not impair the visual cycles in cones. FASEB Journal. January 15:fj201802493R

Cai J, Pires KM, Ferhat M, Chaurasia B, Buffolo MA, Samlling R, Sargsyan A, Atkinson DA, Summers SA, Graham TE, Boudina S (2018). Ablation of autophagy in adipocytes induces insulin resistance and reveals roles for lipid peroxides and Nrf2 signaling in adipose-liver crosstalk. Cell Reports. November; 25(7): 1708-1717

Chaurasia B, Holland WL and Summers SA (2018). Does this schlank make me look fat. Trends in Endocrinology and Metabolism. April; 26(10): 538-50

Chaurasia B#, Kaddai V, Lancaster G, Galam DLA, Gopalan V, Prakash KVB, Bulchand S, Tsong JT, Wang M, Siddique MM, Yuguang G, Sigmundsson K, Mellet NA, Weir J, Meikle P, Hirabayashi Y, Shabeer BMY, Shiow SA, Velan SS and Summers SA (2016). Adipocytes sphingolipids are cell-autonomous regulators of subcutaneous adipose browning, inflammation and metabolic activity. Cell Metabolism. December; 24 (6): 820-834. # Corresponding author.

  • Research Highlight: Fat molecule drop boosts metabolism. Nature. November; 539, 142 (2016).

Jais A, Solas M, Chaurasia B, Backes H, Kleinridders A, Theurich S, Mauer J, Steculorum SS, Hampel B, Goldau J, Alber J, Forster CY, Eming SA, Schwaninger M, Ferrara N, Karsenty G, Brüning J (2016). Myeloid cell-derived VEGF is required to maintain brain glucose uptake and to limit cognitive impairment in obesity. Cell. May; 165(4):882-95.

Chaurasia B & Summers SA (2015). Ceramides-Lipotoxic inducers of metabolic disorders (Review). Trends in Endocrinology and Metabolism. October; 26(10): 538-50.

Siddique M, Ying L, Chaurasia B & Summers SA (2015). Dihydroceramides: from bit players to lead actors (Review). Journal of Biological Chemistry. June; 290(25): 15371-9.

Raichur S, Tein SW, Wee PC, Ying L, Jianhong C, Chaurasia B, Dogra S, Öhman MK, Takeda k, Sugii S, Jung, PY, Futerman AH & Summers SA (2014). CerS2 haploinsufficiency inhibits b-oxidation and confers susceptibility to diet-induced steatohepatitis and insulin resistance. Cell Metabolism. October; 20(7): 687-95

Mauer J#, Chaurasia, B#, Goldau J, Vogt M, Ruud J, Nguyen K, Theurich S, Hausen C, Schmitz J, Brönneke H, Estevez E, Allen T, Mesaros A, Partridge L, Febbraio M, Chawla A, Wünderlich T & Brüning J (2014). Signalling by IL-6 promotes alternative activation of macrophages to limit endotoxemia and obesity-associated resistance to insulin. Nature Immunology. May; 15(5): 423-30. # Co-first authors

Wünderlich C, Deli D, Behnke K, Meryk A, Stroehle P, Chaurasia B, Quraishy S, Wünderlich F, Brüning J and Wunderlich T (2012). Inhibition of IL-6 trans-signaling protects from malaria-induced lethality in mice. J. Immunology. May; 188(9): 4141-4.

Chaurasia B, Mauer J, Koch L, Baumgartel J & Brüning J (2010). PDK-1 provides negative feedback inhibition to TLR-4 mediated NFκB activation in macrophages. Mol Cell Biol. Sep; 30(17): 4354-66.

Mauer J, Chaurasia B, Plum L, Hampel B, Blüher M, Kahn R & Brüning J (2010). Myeloid cell-restricted insulin receptor deficiency protects against obesity-induced inflammation and systemic insulin resistance. PLoS Genet. May 6: e1000938.

Gawlinski P, Nikolay R, Goursot C, Lawo S, Chaurasia B, Herz HM, Kussler-Schneider Y, Ruppert, T, Mayer M & Grosshans, J (2007). The Drosophila mitotic inhibitor Frühstart specifically binds to the hydrophobic patch of cyclins. EMBO reports, 8(5): 490-496.